SCHEMBL1203382

SCHEMBL1203382

CO[Si](Br)(c1ccccc1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
CA4 P22748 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705909 0.77 MAPK1 (0.39) MAPK1CA4ALDH1A1ALOX15ESR1
SCHEMBL277279 0.73 MAPK1 (0.36) MAPK1CA4ALDH1A1ALOX15ESR1
SCHEMBL704188 0.73 MAPK1 (0.36) MAPK1CA4ALDH1A1ALOX15ESR1
SCHEMBL702695 0.73 MAPK1 (0.36) MAPK1CA4ALDH1A1ALOX15ESR1
SCHEMBL17835393 0.72 CA4 (0.38) MAPK1CA4ALDH1A1ESR1ESR2
SCHEMBL703364 0.72 ESR1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL708032 0.72 NR1H2 (0.36) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL18108221 0.72 CA4 (0.38) MAPK1CA4ALDH1A1ESR1ESR2
SCHEMBL18108065 0.72 CA4 (0.38) MAPK1CA4ALDH1A1ESR1ESR2
SCHEMBL1313821 0.71 ESR1 (0.35) MAPK1CA4ALDH1A1ALOX15ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113045803-A Antioxidant modified plastic particles and application thereof 界首市宏佳塑业有限公司 2021-06-29 CN claimed
CN-107214808-B Composite wood and its manufacturing method 浙江润格木业科技有限公司 2019-06-07 CN claimed
EP-1343766-B1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES PROCTER & GAMBLE (US) 2005-07-27 EP claimed
EP-1532114-A2 PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES THE PROCTER & GAMBLE COMPANY (US) 2005-05-25 EP claimed
US-6803469-B2 CYCLIZING IN THE PRESENCE OF A SILYLATING AGENT THE PROCTER & GAMBLE COMPANY 2004-10-12 US claimed
US-20040063952-A1 Process for preparing quinolone antibiotic intermediates WARNER CHILCOTT COMPANY, LLC 2004-04-01 US claimed
WO-2004013103-A2 PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES THE PROCTER & GAMBLE COMPANY (US) 2004-02-12 WO claimed
EP-1343766-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2003-09-17 EP claimed
WO-2002048113-A1 CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES THE PROCTER & GAMBLE COMPANY (US) 2002-06-20 WO claimed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-11572434-B2 Curable composition, method for producing same, and article using same DAIKIN INDUSTRIES, LTD. (JP) 2023-02-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
CN-113045803-A Antioxidant modified plastic particles and application thereof 界首市宏佳塑业有限公司 2021-06-29 CN disclosed
CN-113045803-A Antioxidant modified plastic particles and application thereof 界首市宏佳塑业有限公司 2021-06-29 CN disclosed
US-5703231-A Process for making antimicrobial compounds THE PROCTER & GAMBLE COMPANY (US) 1997-12-30 US disclosed
EP-0775145-A1 PROCESS FOR MAKING QUINOLONYL LACTAM ANTIMICROBIALS AND NOVEL INTERMEDIATE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1997-05-28 EP disclosed
EP-0775114-A1 PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1997-05-28 EP disclosed
WO-1996004286-A9 PROCESS FOR MAKING QUINOLONYL LACTAM ANTIMICROBIALS AND NOVEL INTERMEDIATE COMPOUNDS 1997-05-22 WO disclosed
WO-1996004247-A1 PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-02-15 WO disclosed
WO-1996004286-A1 PROCESS FOR MAKING QUINOLONYL LACTAM ANTIMICROBIALS AND NOVEL INTERMEDIATE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063952-A1 Process for preparing quinolone antibiotic intermediates QPCT, CCNT1, TOP1 MAPK1 1045/4885CA4 1757/4885ALDH1A1 751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.