Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 4/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | GABRP | O00591 | 5/20 | 0.35 |
| ▸ | GABRD | O14764 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.35 |
| ▸ | GABRE | P78334 | 5/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202649 | 0.91 | CA12 (0.41) | CXCL12CSNK2A1ACHEBACE1BCHE | |
| SCHEMBL27462 | 0.91 | CA12 (0.41) | CXCL12CSNK2A1ACHEBACE1BCHE | |
| Hydrochloric Acid SCHEMBL1734541 | 0.90 | CA12 (0.40) | CXCL12CSNK2A1ACHEBACE1BCHE | |
| SCHEMBL6055777 | 0.85 | CA12 (0.40) | CXCL12CSNK2A1ACHEBACE1BCHE | |
| SCHEMBL6055900 | 0.84 | GABRP (0.37) | CSNK2A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL6055915 | 0.83 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12045251 | 0.83 | CA12 (0.39) | CXCL12CSNK2A1ACHEBACE1BCHE | |
| SCHEMBL6055715 | 0.82 | GAA (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7825820 | 0.81 | LMNA (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055784 | 0.81 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609871-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-04-04 | — | — | US | disclosed |
| EP-2104426-B1 | AGENTS FOR CONTROLLING PARASITES ON ANIMALS | BAYER IP GMBH (DE) | 2016-03-30 | — | — | EP | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-20160007611-A1 | Combination product for controlling parasites on animals | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9137995-B2 | Combination product for controlling parasites on animals | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20130012562-A1 | Composition for Controlling Parasites on Animals | BAYER ANIMAL HEALTH GMBH (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20130012562-A1 | Composition for Controlling Parasites on Animals | BAYER ANIMAL HEALTH GMBH (DE) | 2013-01-10 | — | — | US | disclosed |
| US-8071116-B2 | Combination product for controlling parasites on animals | BAYER ANIMAL HEALTH GMBH (DE) | 2011-12-06 | — | — | US | disclosed |
| US-8071116-B2 | Combination product for controlling parasites on animals | BAYER ANIMAL HEALTH GMBH (DE) | 2011-12-06 | — | — | US | disclosed |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2008080541-A1 | AGENTS FOR CONTROLLING PARASITES ON ANIMALS | BAYER ANIMAL HEALTH GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007611-A1 | Combination product for controlling parasites on animals | CYCS, CYP3A43, CDIPT | CXCL12 4843/4885CSNK2A1 3133/4885ACHE 410/4885 |
| US-20100016398-A1 | COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS | CYCS, CYP3A43, CDIPT | CXCL12 4843/4885CSNK2A1 3133/4885ACHE 410/4885 |
| US-20090312387-A1 | COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS | CYCS, PTMS, PLCB3 | CXCL12 4385/4885CSNK2A1 1547/4885ACHE 1113/4885 |
| US-20130012562-A1 | Composition for Controlling Parasites on Animals | CYCS, PTMS, PLCB3 | CXCL12 4385/4885CSNK2A1 1547/4885ACHE 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.