Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945858 | 0.81 | CES1 (0.58) | CES1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27369755 | 0.72 | TDP1 (0.58) | CES1ALDH1A1MAPK1KMT2AHDAC8 | |
| Water SCHEMBL27403515 | 0.71 | TDP1 (0.56) | CES1ALDH1A1MAPK1KMT2AHDAC8 | |
| SCHEMBL4658964 | 0.70 | CES1 (0.47) | CES1ALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL4753311 | 0.70 | CES1 (0.71) | CES1L3MBTL1CES2AKR1B1MEN1 | |
| Trifluoroacetic Acid SCHEMBL27623336 | 0.67 | CES1 (0.56) | CES1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5150815 | 0.67 | HDAC8 (0.57) | CES1ALDH1A1MAPK1L3MBTL1CES2 | |
| SCHEMBL51367 | 0.66 | CES1 (0.64) | CES1ALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27694802 | 0.66 | ALDH1A1 (0.50) | CES1ALDH1A1MAPK1L3MBTL1MEN1 | |
| SCHEMBL8052310 | 0.66 | CES1 (0.65) | CES1CRHBPCRHR2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319594-A1 | METHOD FOR PRODUCING BIVALIRUDIN | SHANGHAI AMBIOPHARM, INC. (CN) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319594-A1 | METHOD FOR PRODUCING BIVALIRUDIN | ARGLU1, SERPINC1, PSMA6 | CES1 4402/4885CRHBP 231/4885CRHR2 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.