Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844153 | 0.75 | POLB (0.36) | POLBALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL9155883 | 0.75 | POLB (0.36) | POLBALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL11853813 | 0.73 | POLB (0.35) | POLBALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL11837510 | 0.73 | POLB (0.35) | POLBALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL13134078 | 0.71 | CHRNB2 (0.44) | POLBALDH1A1KDM4EMAPTGAA | |
| Dimethylamine SCHEMBL11879381 | 0.71 | POLB (0.33) | POLBALDH1A1KDM4EMAPTHCRTR1 | |
| SCHEMBL7738583 | 0.70 | LMNA (0.40) | POLBALDH1A1KDM4EGAAMTOR | |
| SCHEMBL13032863 | 0.70 | ALDH1A1 (0.33) | ALDH1A1ADORA3L3MBTL1 | |
| SCHEMBL11616050 | 0.69 | ALDH1A1 (0.41) | POLBALDH1A1KDM4EGAACYP1A2 | |
| SCHEMBL17863680 | 0.68 | HPGD (0.39) | ALDH1A1MAPTMTORMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718790-B2 | Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9688643-B2 | Triazine derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20160185736-A1 | NOVEL, TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SHIONOGI & CO., LTD. | 2016-06-30 | — | — | US | disclosed |
| US-9150546-B2 | Triazine derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20130172317-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION HAVING AN ANALGESIC ACTIVITY COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| US-20110319414-A1 | NOVEL TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185736-A1 | NOVEL, TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | P2RX3, P2RX5, P2RX2 | POLB 2502/4885ALDH1A1 1636/4885KDM4E 3209/4885 |
| US-20110319414-A1 | NOVEL TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | P2RX3, P2RX5, P2RX2 | POLB 2421/4885ALDH1A1 1707/4885KDM4E 3370/4885 |
| US-20130172317-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION HAVING AN ANALGESIC ACTIVITY COMPRISING THE SAME | P2RX3, P2RX4, P2RX2 | POLB 2243/4885ALDH1A1 2167/4885KDM4E 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.