SCHEMBL12047987

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12047821	0.98	TDP1 (0.47)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048453	0.96	TDP1 (0.45)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048325	0.94	TDP1 (0.44)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048554	0.93	TDP1 (0.43)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048043	0.93	TDP1 (0.43)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048748	0.92	TDP1 (0.54)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL13136843	0.92	CYP2A6 (0.52)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL5571565	0.92	CYP2A6 (0.52)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048103	0.92	TDP1 (0.42)	TDP1MAPTNR1I2LMNACYP1A2
	SCHEMBL12048586	0.91	TDP1 (0.41)	TDP1MAPTNR1I2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.