SCHEMBL12048751

SCHEMBL12048751

COc1ccc(N(C)c2ccc3ccccc3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CYP2A6 P11509 1/20 0.59
EGFR P00533 3/20 0.48
PDGFRB P09619 3/20 0.48
KDR P35968 3/20 0.48
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
NQO2 P16083 1/20 0.46
CASP3 P42574 2/20 0.45
CES1 P23141 1/20 0.45
CASP1 P29466 1/20 0.45
CASP14 P31944 1/20 0.45
CASP2 P42575 1/20 0.45
CASP4 P49662 1/20 0.45
CASP5 P51878 1/20 0.45
CASP7 P55210 1/20 0.45
CASP9 P55211 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12047972 0.91 CYP1A2 (0.53) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL12047823 0.89 CYP1A2 (0.50) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL13367666 0.88 CYP1A2 (0.53) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL12048454 0.87 CYP1A2 (0.49) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL5441435 0.86 HTT (0.49) CYP1A2CYP2A6HTTTDP1L3MBTL1
SCHEMBL12048752 0.86 MTNR1A (0.55) CYP1A2CYP2A6NQO2NPC1MTNR1A
SCHEMBL12048045 0.85 CYP1A2 (0.46) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL12048328 0.85 CYP1A2 (0.46) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL12048556 0.85 CYP1A2 (0.46) CYP1A2CYP2A6EGFRPDGFRBKDR
SCHEMBL13367394 0.84 CYP1A2 (0.44) CYP1A2CYP2A6EGFRPDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028977-B2 Compound, method for preparing same and organic electronic device using same LG CHEM, LTD. (KR) 2015-05-12 US disclosed
US-9028977-B2 Compound, method for preparing same and organic electronic device using same LG CHEM, LTD. (KR) 2015-05-12 US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 US disclosed
US-8968884-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2015-03-03 US disclosed
US-8431246-B2 Organic metal complexs derivative and organic light emitting device using the same LG CHEM, LTD. (KR) 2013-04-30 US disclosed
US-8431246-B2 Organic metal complexs derivative and organic light emitting device using the same LG CHEM, LTD. (KR) 2013-04-30 US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 US disclosed
US-8410475-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2013-04-02 US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 US disclosed
US-8071227-B2 Compounds and organic light emitting diode using the same LG CHEM, LTD. (KR) 2011-12-06 US disclosed
WO-2008066357-A1 NEW COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2008-06-05 WO disclosed
WO-2008066358-A1 NEW COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME LG CHEM, LTD. (KR) 2008-06-05 WO disclosed
US-20080008907-A1 Compound And Organic Light Emitting Device Using The Same LG CHEM, LTD. (PROSECUTION) (KR) 2008-01-10 US disclosed
US-20080008907-A1 Compound And Organic Light Emitting Device Using The Same LG CHEM, LTD. (PROSECUTION) (KR) 2008-01-10 US disclosed
US-20070292715-A1 New Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-12-20 US disclosed
US-20070292715-A1 New Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-12-20 US disclosed
US-20070262706-A1 New Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-11-15 US disclosed
US-20070262706-A1 New Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-11-15 US disclosed
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-10-25 US disclosed
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070247059-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 CYP1A2 1160/4885CYP2A6 1916/4885EGFR 4003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.