SCHEMBL12048752

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12047979	0.92	MTNR1A (0.52)	MTNR1AMTNR1BCYP1A2CYP2A6NQO2
	SCHEMBL12047826	0.91	MTNR1A (0.51)	MTNR1AMTNR1BCYP1A2CYP2A6KDM4C
	SCHEMBL12048458	0.89	MTNR1A (0.49)	MTNR1AMTNR1BCYP1A2CYP2A6KDM4C
	SCHEMBL12048332	0.87	MTNR1A (0.48)	MTNR1AMTNR1BCYP1A2CYP2A6KDM4C
	SCHEMBL1134082	0.87	MTNR1A (0.61)	MTNR1AMTNR1BHSD17B2HSD17B1ACHE
	SCHEMBL30054343	0.87	MTNR1A (0.61)	MTNR1AMTNR1BHSD17B2HSD17B1ACHE
	SCHEMBL12048557	0.86	MTNR1A (0.47)	MTNR1AMTNR1BCYP1A2CYP2A6KDM4C
	SCHEMBL12048046	0.86	MTNR1A (0.47)	MTNR1AMTNR1BCYP1A2CYP2A6KDM4C
	SCHEMBL12048751	0.86	CYP1A2 (0.59)	MTNR1AMTNR1BCYP1A2CYP2A6NQO2
	SCHEMBL1134087	0.85	MTNR1A (0.60)	MTNR1AMTNR1BHSD17B2HSD17B1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.