Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.69 |
| ▸ | CA1 | P00915 | 15/20 | 0.69 |
| ▸ | CA2 | P00918 | 15/20 | 0.69 |
| ▸ | CA12 | O43570 | 6/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ELF3 | P78545 | 1/20 | 0.54 |
| ▸ | MED23 | Q9ULK4 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23205535 | 0.94 | DNASE1L3 (0.63) | CA9CA1CA2CA12USP2 | |
| SCHEMBL21128728 | 0.93 | CA9 (0.67) | CA9CA1CA2CA12USP2 | |
| SCHEMBL23762521 | 0.91 | CA9 (0.66) | CA9CA1CA2CA12USP2 | |
| SCHEMBL12231957 | 0.90 | CA9 (0.72) | CA9CA1CA2CA12USP2 | |
| SCHEMBL15828111 | 0.89 | CA9 (0.83) | CA9CA1CA2CA12USP2 | |
| SCHEMBL18470198 | 0.89 | CA9 (0.72) | CA9CA1CA2CA12USP2 | |
| SCHEMBL13083473 | 0.88 | CA9 (0.55) | CA9CA1CA2CA12USP2 | |
| SCHEMBL13097493 | 0.88 | CA9 (0.75) | CA9CA1CA2CA12USP2 | |
| SCHEMBL19954964 | 0.88 | CA9 (0.72) | CA9CA1CA2CA12USP2 | |
| SCHEMBL12060447 | 0.88 | CA9 (0.75) | CA9CA1CA2CA12USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174576-A1 | BETA-STRAND BRIDGE PEPTIDE | KYOTO UNIVERSITY (JP) | 2023-06-08 | — | — | US | disclosed |
| US-20230174576-A1 | BETA-STRAND BRIDGE PEPTIDE | KYOTO UNIVERSITY (JP) | 2023-06-08 | — | — | US | disclosed |
| US-11332496-B2 | Stapled and stitched polypeptides and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-05-17 | — | — | US | disclosed |
| WO-2021062176-A2 | POLYMERIC TANDEM DYES WITH LINKER GROUPS | SONY CORPORATION (JP) | 2021-04-01 | — | — | WO | disclosed |
| US-10919936-B2 | — | — | 2021-02-16 | — | — | US | disclosed |
| US-20200308231-A9 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-01 | — | — | US | disclosed |
| US-20190300576-A1 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-10-03 | — | — | US | disclosed |
| US-10301351-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180057565-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-01 | — | — | US | disclosed |
| US-9556227-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556227-B2 | Stitched polypeptides | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-31 | — | — | US | disclosed |
| US-9487562-B2 | Stabilized polypeptides as regulators of RAB GTPase function | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160024153-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-01-28 | — | — | US | disclosed |
| US-20150225471-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-08-13 | — | — | US | disclosed |
| US-20140235549-A1 | STABILIZED POLYPEPTIDES AS REGULATORS OF RAB GTPASE FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140011979-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |
| EP-2508531-A1 | Stitched polypeptides | President and Fellows of Harvard College (US) | 2012-10-10 | — | — | EP | disclosed |
| US-20110321183-A1 | METHODS FOR LIGATION AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2011-12-29 | — | — | US | disclosed |
| US-20100184645-A1 | STITCHED POLYPEPTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225471-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | IAPP, GLP1R, INSR | CA9 3533/4885CA1 4509/4885CA2 4457/4885 |
| US-20200308231-A9 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | TP53, MDM2, MDM4 | CA9 2395/4885CA1 294/4885CA2 1282/4885 |
| US-20190300576-A1 | SOLUTION-PHASE AFFINITY SELECTION OF INHIBITORS FROM COMBINATORIAL PEPTIDE LIBRARIES | TP53, MDM2, MDM4 | CA9 2395/4885CA1 294/4885CA2 1282/4885 |
| US-20100184645-A1 | STITCHED POLYPEPTIDES | VIP, IAPP, NGLY1 | CA9 2138/4885CA1 3243/4885CA2 3939/4885 |
| US-10301351-B2 | Stitched polypeptides | VIP, IAPP, NGLY1 | CA9 2138/4885CA1 3243/4885CA2 3939/4885 |
| US-20160024153-A1 | STAPLED AND STITCHED POLYPEPTIDES AND USES THEREOF | VIP, NGLY1, F13A1 | CA9 1529/4885CA1 879/4885CA2 3716/4885 |
| US-20230174576-A1 | BETA-STRAND BRIDGE PEPTIDE | IAPP, SPPL2B, VIP | CA9 3180/4885CA1 1659/4885CA2 3885/4885 |
| US-10919936-B2 | — | VIP, NGLY1, F12 | CA9 1921/4885CA1 654/4885CA2 3278/4885 |
| US-20140235549-A1 | STABILIZED POLYPEPTIDES AS REGULATORS OF RAB GTPASE FUNCTION | RHEB, RABL3, RIN1 | CA9 4091/4885CA1 4297/4885CA2 4179/4885 |
| US-20140011979-A1 | STITCHED POLYPEPTIDES | VIP, IAPP, NGLY1 | CA9 2138/4885CA1 3243/4885CA2 3939/4885 |
| US-20180057565-A1 | STABILIZED POLYPEPTIDE INSULIN RECEPTOR MODULATORS | IAPP, GLP1R, INSR | CA9 3565/4885CA1 4513/4885CA2 4476/4885 |
| US-11332496-B2 | Stapled and stitched polypeptides and uses thereof | VIP, NGLY1, IAPP | CA9 1811/4885CA1 1006/4885CA2 3765/4885 |
| US-20110321183-A1 | METHODS FOR LIGATION AND USES THEREOF | ACOT7, LYPLA1, ACSL3 | CA9 1483/4885CA1 2809/4885CA2 3793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.