Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12062503 | 0.89 | L3MBTL1 (0.49) | L3MBTL1RAB9ATSHRCASP3SENP8 | |
| SCHEMBL12062502 | 0.81 | KMT2A (0.43) | L3MBTL1TSHRATMKMT2AMEN1 | |
| SCHEMBL5812840 | 0.80 | CNR2 (0.59) | L3MBTL1SPHK2MAPK8HPGDALDH1A1 | |
| SCHEMBL4448177 | 0.79 | ATM (0.49) | ATMKMT2AMEN1HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL9313499 | 0.75 | HPGD (0.61) | RAB9AATMKMT2AMEN1HPGD | |
| SCHEMBL5717635 | 0.71 | ALDH1A1 (0.73) | KMT2AMAPK8ALDH1A1TDP1 | |
| SCHEMBL5717798 | 0.71 | ALDH1A1 (0.61) | RAB9AATMPOLBKMT2AMEN1 | |
| SCHEMBL2820683 | 0.70 | LMNA (0.61) | TSHRSPHK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5485588 | 0.70 | LMNA (0.61) | TSHRSPHK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7311813 | 0.69 | MEN1 (0.53) | L3MBTL1RAB9AKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076372-B2 | Acythiols and component thiol compositions as anti-HIV and anti-retroviral agents | GOVERNMENT OF THE UNITED STATES (US) | 2011-12-13 | — | — | US | disclosed |
| US-20090247473-A1 | ACYTHIOLS AND COMPONENT THIOL COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | THE GOVERNMENT OF THE U.S.A.,AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES (US) | 2009-10-01 | — | — | US | disclosed |
| US-7528274-B2 | Acylthiols and component thiol compositions as anti-HIV and anti-retroviral agents | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247473-A1 | ACYTHIOLS AND COMPONENT THIOL COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | ZC3HAV1, ZFP3, ATL3 | L3MBTL1 340/4885RAB9A 3502/4885TSHR 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.