Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770551 | 0.89 | LMNA (0.43) | LMNAKDM4EALDH1A1MAPTOPRM1 | |
| SCHEMBL14774196 | 0.89 | MLKL (0.42) | MLKLLMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14770730 | 0.72 | MLKL (0.44) | MLKLLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL14770549 | 0.71 | ALDH1A1 (0.42) | MLKLLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL14770499 | 0.69 | MLKL (0.44) | MLKLLMNAKDM4EALDH1A1ROCK2 | |
| SCHEMBL12066053 | 0.68 | MLKL (0.41) | MLKLLMNAKDM4EALDH1A1ROCK2 | |
| SCHEMBL691734 | 0.68 | ALDH1A1 (0.73) | LMNAALDH1A1MAPTOPRM1OPRD1 | |
| SCHEMBL14762836 | 0.68 | MLKL (0.48) | MLKLKDM4EALDH1A1 | |
| SCHEMBL14770690 | 0.67 | MLKL (0.52) | MLKLLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL14770550 | 0.67 | FLT3 (0.40) | MLKLLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148956-A1 | FUSED IMIDAZOLE DERIVATIVE | トーアエイヨー株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |