Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215323 | 0.82 | SCD (0.41) | SCDNPSR1HSD17B13PRSS12HPGD | |
| SCHEMBL12068101 | 0.80 | RAB9A (0.40) | HSD17B13HPGDTSHR | |
| SCHEMBL10215325 | 0.77 | SCD (0.40) | SCDNPSR1HSD17B13PRSS12HPGD | |
| SCHEMBL10216308 | 0.76 | SCD (0.42) | SCDNPSR1HSD17B13PRSS12HPGD | |
| SCHEMBL10215314 | 0.76 | SCD (0.42) | SCDNPSR1 | |
| SCHEMBL12068100 | 0.76 | KDM4E (0.44) | NPSR1HPGDTSHR | |
| SCHEMBL12068693 | 0.73 | PTGES (0.38) | HPGDTSHR | |
| SCHEMBL12068644 | 0.69 | ALDH1A1 (0.41) | SCDHPGDTSHR | |
| SCHEMBL10216317 | 0.65 | RAB9A (0.52) | HPGD | |
| SCHEMBL12066540 | 0.64 | RBP4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156610-A2 | INHIBITORS OF HEPATITIS C VIRUS | GILEAD SCIENCES, INC. (US) | 2011-12-15 | — | — | WO | disclosed |