SCHEMBL12083455

SCHEMBL12083455

Cc1cccc2c1N1C(=CN(C)C1C)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ DPP4 P27487 1/20 0.33
▸ MAPT P10636 2/20 0.30
▸ LMNA P02545 1/20 0.30
▸ MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9891022 1.00 ALDH1A1 (0.36) ALDH1A1KMT2AMEN1POLBDPP4
SCHEMBL19680274 0.74 DPP4 (0.34) ALDH1A1KMT2AMEN1POLBDPP4
SCHEMBL18708643 0.72 HTR2C (0.33) ALDH1A1KMT2AMEN1POLBDPP4
SCHEMBL17952359 0.71 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1POLB
SCHEMBL13875989 0.69 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1POLBMAPT
SCHEMBL20627486 0.69 ALDH1A1 (0.31) ALDH1A1DPP4
SCHEMBL13969349 0.67 NISCH (0.34) ALDH1A1KMT2AMEN1POLB
SCHEMBL17952209 0.67 CYP1A2 (0.33) ALDH1A1KMT2AMEN1POLB
SCHEMBL13875971 0.66 HTR2C (0.35) —
SCHEMBL11921038 0.65 MEN1 (0.34) ALDH1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818948-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 — — US disclosed
US-11692131-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes UDC IRELAND LIMITED (IE) 2023-07-04 — — US disclosed
US-11692131-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes UDC IRELAND LIMITED (IE) 2023-07-04 — — US disclosed
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues UNITED STATES DEPARTMENT OF ENERGY 2020-04-16 — — US disclosed
US-20190322929-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES UDC IRELAND LTD (IE) 2019-10-24 — — US disclosed
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 — — US disclosed
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 — — US disclosed
US-8877937-B2 Process for preparing transition metal-carbene complexes BASF SE (DE) 2014-11-04 — — US disclosed
US-8877937-B2 Process for preparing transition metal-carbene complexes BASF SE (DE) 2014-11-04 — — US disclosed
US-8728632-B2 Metal complexes comprising bridged carbene ligands and use thereof in OLEDs BASF SE (DE) 2014-05-20 — — US disclosed
US-8383828-B2 Transition metal complexes comprising one noncarbene ligand and one or two carbene ligands and their use in OLEDs BASF AKTIENGESELLSCHAFT (DE) 2013-02-26 — — US disclosed
US-8258297-B2 Transition metal complexes with bridged carbene ligands and use thereof in OLEDs BASF SE (DE) 2012-09-04 — — US disclosed
EP-2338593-A1 Process for the preparation of transition metal carbene complexes BASF SE (DE) 2011-06-29 — — EP disclosed
US-20100264405-A1 TRANSITION METAL COMPLEXES WITH BRIDGED CARBENE LIGANDS AND USE THEREOF IN OLEDS BASF SE (DE) 2010-10-21 — — US disclosed
US-20100213834-A1 TRANSITION METAL COMPLEXES COMPRISING BRIDGED CARBENE LIGANDS AND USE THEREOF IN OLEDS BASF SE (DE) 2010-08-26 — — US disclosed
US-20090096367-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) BASF SE (DE) 2009-04-16 — — US disclosed
US-20090054657-A1 Transition Metal Complexes Comprising One Noncarbene Ligand and One or Two Carbene Ligands and their Use in Oleds BASF SE (DE) 2009-02-26 — — US disclosed
US-20090018330-A1 PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES BASF SE (DE) 2009-01-15 — — US disclosed
US-20090018330-A1 PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES BASF SE (DE) 2009-01-15 — — US disclosed
WO-2007088093-A1 PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES BASF SE (DE) 2007-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018330-A1 PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES AP1M1, C1S, GPS1 ALDH1A1 2893/4885KMT2A 2456/4885MEN1 51/4885
US-20090096367-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) OCIAD2, OCIAD1, ICOSLG ALDH1A1 1119/4885KMT2A 3028/4885MEN1 3745/4885
US-20190322929-A1 HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES CLTB, CLTC, CYBA ALDH1A1 1498/4885KMT2A 2033/4885MEN1 2607/4885
US-20090054657-A1 Transition Metal Complexes Comprising One Noncarbene Ligand and One or Two Carbene Ligands and their Use in Oleds OCIAD1, OCIAD2, ICOSLG ALDH1A1 1163/4885KMT2A 3313/4885MEN1 3677/4885
US-11818948-B2 Organic electroluminescent materials and devices SLCO4C1, SLC29A1, SLC29A2 ALDH1A1 1044/4885KMT2A 1491/4885MEN1 1698/4885
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues IK, HELZ, SUN2 ALDH1A1 1492/4885KMT2A 453/4885MEN1 3029/4885
US-11692131-B2 Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes CLTB, CLTC, CYBA ALDH1A1 1498/4885KMT2A 2033/4885MEN1 2607/4885
US-20100213834-A1 TRANSITION METAL COMPLEXES COMPRISING BRIDGED CARBENE LIGANDS AND USE THEREOF IN OLEDS OCIAD1, OCIAD2, OPRD1 ALDH1A1 696/4885KMT2A 3450/4885MEN1 4325/4885
US-20100264405-A1 TRANSITION METAL COMPLEXES WITH BRIDGED CARBENE LIGANDS AND USE THEREOF IN OLEDS OCIAD1, OCIAD2, OPRD1 ALDH1A1 656/4885KMT2A 3439/4885MEN1 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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