Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27647919 | 0.75 | ALOX5 (0.46) | SMN1; SMN2CYP1A2ALDH1A1KDM4E | |
| SCHEMBL2929113 | 0.75 | CTSK (0.42) | FPR2CTSKCTSSSMN1; SMN2CYP1A2 | |
| SCHEMBL13528673 | 0.72 | ALDH1A1 (0.51) | CTSKCTSSSMN1; SMN2ALDH1A1AAK1 | |
| SCHEMBL5877530 | 0.70 | AAK1 (0.50) | FPR2CTSKCTSSSMN1; SMN2CYP1A2 | |
| SCHEMBL255676 | 0.70 | AAK1 (0.50) | FPR2CTSKCTSSSMN1; SMN2CYP1A2 | |
| SCHEMBL2552301 | 0.70 | AAK1 (0.50) | FPR2CTSKCTSSSMN1; SMN2CYP1A2 | |
| SCHEMBL29748714 | 0.69 | ALDH1A1 (0.39) | FPR2CTSKSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL20556121 | 0.69 | ALDH1A1 (0.39) | FPR2CTSKSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL18492925 | 0.69 | ALDH1A1 (0.39) | FPR2CTSKSMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL18501654 | 0.69 | ALDH1A1 (0.39) | FPR2CTSKSMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046105-A1 | Heterocycle-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising them and use thereof | SANOFI-AVENTIS (FR) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046105-A1 | Heterocycle-substituted imidazolidine-2,4-diones, process for preparation thereof, medicaments comprising them and use thereof | GIPR, DDC, PGC | FPR2 3038/4885CTSK 1190/4885CTSS 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.