Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257733 | 0.91 | ELANE (0.47) | ELANEF2PLAU | |
| SCHEMBL9959564 | 0.90 | ELANE (0.47) | ELANEF2PLAU | |
| SCHEMBL9959964 | 0.90 | ELANE (0.47) | ELANEF2PLAU | |
| SCHEMBL257431 | 0.86 | ELANE (0.44) | ELANEF2PLAU | |
| SCHEMBL2237767 | 0.83 | HTR3A (0.46) | ELANE | |
| SCHEMBL12090385 | 0.82 | LMNA (0.41) | — | |
| SCHEMBL12090323 | 0.81 | KDM4E (0.37) | ELANE | |
| SCHEMBL16125889 | 0.81 | ELANE (0.41) | ELANEF2PLAUCTRB1 | |
| SCHEMBL2239274 | 0.80 | ELANE (0.45) | ELANEF2PLAU | |
| SCHEMBL6207155 | 0.80 | ELANE (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ADRB3, ADRB1, ADRB2 | ELANE 1921/4885F2 3937/4885PLAU 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.