Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463596 | 0.89 | KMT2A (0.48) | KMT2APHGDHALDH1A1SMN1; SMN2PIN1 | |
| SCHEMBL2225281 | 0.87 | PHGDH (0.43) | KMT2APHGDHALDH1A1SMN1; SMN2PIN1 | |
| SCHEMBL1464318 | 0.87 | HSD11B1 (0.51) | KMT2AALDH1A1SMN1; SMN2PIN1MAPT | |
| SCHEMBL766844 | 0.86 | NOD2 (0.44) | KMT2APHGDHALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL469434 | 0.86 | ABCB11 (0.55) | KMT2APHGDHTHRBMAPTABCB11 | |
| SCHEMBL1464174 | 0.84 | MMP13 (0.50) | ALDH1A1SMN1; SMN2MMP8ABCB11CYP1A2 | |
| SCHEMBL1464437 | 0.84 | MMP1 (0.45) | KMT2APHGDHPIN1HSD11B1MMP8 | |
| SCHEMBL1464602 | 0.83 | CNR2 (0.50) | KMT2APHGDHMAPTRORCTSHR | |
| SCHEMBL19692913 | 0.82 | HSD11B1 (0.42) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL26966928 | 0.81 | ELANE (0.50) | KMT2AELANECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |