SCHEMBL12106916

SCHEMBL12106916

CCC(=O)Nc1cc(Cl)c(C)c(Cl)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 7/20 0.46
KDM4E B2RXH2 4/20 0.46
PKM P14618 2/20 0.46
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
CCR6 P51684 1/20 0.46
MCL1 Q07820 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
CYP3A4 P08684 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GFER P55789 1/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179594 0.88 POLB (0.52) TSHRALDH1A1KDM4EPKMLMNA
SCHEMBL6944416 0.87 ALDH1A1 (0.47) ALDH1A1KDM4EPKMMAPTLMNA
SCHEMBL6416431 0.83 GPR35 (0.44) TSHRALDH1A1MAPTKMT2AMEN1
SCHEMBL12260118 0.83 L3MBTL1 (0.48) ALDH1A1KDM4EMAPTMAPK1KMT2A
SCHEMBL10942210 0.83 L3MBTL1 (0.48) ALDH1A1KDM4EMAPTMAPK1KMT2A
SCHEMBL13295188 0.83 CYP3A4 (0.44) TSHRALDH1A1KDM4EPKMMAPT
SCHEMBL6439722 0.82 SMN1; SMN2 (0.48) TSHRALDH1A1KDM4EPKMLMNA
SCHEMBL7027625 0.81 ALDH1A1 (0.41) ALDH1A1KDM4EMAPTLMNAKMT2A
SCHEMBL14563706 0.79 KMT2A (0.40) CYP3A4KMT2AMEN1RAB9AHTT
SCHEMBL6944637 0.79 ALDH1A1 (0.52) ALDH1A1MAPTMAPK1ATMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8052785-B2 Polymer containing image receiver sheet on support FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER INMT, TYR, IK TSHR 1060/4885ALDH1A1 401/4885KDM4E 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.