Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12846467 | 0.85 | MEN1 (0.35) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL12106916 | 0.82 | TSHR (0.46) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL6944416 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL9179594 | 0.76 | POLB (0.52) | HTTLMNAKDM4EALDH1A1POLB | |
| SCHEMBL11054920 | 0.75 | KDM4E (0.36) | HTTLMNAKDM4EALDH1A1THRA | |
| SCHEMBL6416431 | 0.75 | GPR35 (0.44) | ALDH1A1HSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL10448522 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| SCHEMBL6944637 | 0.74 | ALDH1A1 (0.52) | HTTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL7027625 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2HTTLMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6942166 | 0.73 | ALDH1A1 (0.54) | HTTLMNAALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846844-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| US-20030220226-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220226-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | SMN1; SMN2 119/4885HTT 547/4885LMNA 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.