SCHEMBL12106917

SCHEMBL12106917

CCC(=O)NC1=CC(=Nc2ccc(N(CC)CC)cc2)C(C)=C(Cl)C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.36
ALDH1A1 P00352 6/20 0.35
MAPK1 P28482 3/20 0.35
KDM4E B2RXH2 3/20 0.35
MCL1 Q07820 3/20 0.35
NPSR1 Q6W5P4 3/20 0.35
LMNA P02545 3/20 0.35
ATM Q13315 2/20 0.35
PKM P14618 1/20 0.35
CCR6 P51684 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
HTT P42858 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12106911 0.94 GHSR (0.36) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL12106903 0.92 HDAC3 (0.37) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL12106921 0.90 ALDH1A1 (0.38) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL92428 0.87 MAPT (0.39) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL12106904 0.87 CNR2 (0.41) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL12106922 0.87 CNR2 (0.40) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL17342959 0.85 GFER (0.36) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL14157756 0.85 ESRRG (0.43) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL12106906 0.84 GHSR (0.36) MAPTALDH1A1MAPK1KDM4EMCL1
SCHEMBL92900 0.84 RAB9A (0.35) MAPTALDH1A1MAPK1KDM4EMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8052785-B2 Polymer containing image receiver sheet on support FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER INMT, TYR, IK MAPT 389/4885ALDH1A1 401/4885MAPK1 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.