SCHEMBL12106921

SCHEMBL12106921

CCN(CC)c1ccc(N=C2C=C(NC(C)=O)C(=O)C(Cl)=C2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
TSHR P16473 4/20 0.38
MAPT P10636 10/20 0.36
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
GAA P10253 4/20 0.36
MCL1 Q07820 3/20 0.36
NOX1 Q9Y5S8 3/20 0.36
POLB P06746 2/20 0.36
HTT P42858 4/20 0.36
MAPK1 P28482 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12106906 0.94 GHSR (0.36) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL12106907 0.92 MAPT (0.32) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL56041 0.91 RORC (0.32) CNR2ESRRG
SCHEMBL12106917 0.90 MAPT (0.36) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL12106922 0.88 CNR2 (0.40) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL12106903 0.88 HDAC3 (0.37) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL92428 0.88 MAPT (0.39) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL12106904 0.88 CNR2 (0.41) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL14157756 0.86 ESRRG (0.43) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL10000297 0.85 POLB (0.36) ALDH1A1TSHRMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8052785-B2 Polymer containing image receiver sheet on support FUJIFILM CORPORATION (JP) 2011-11-08 US disclosed
US-8017551-B2 Multilayer; support, vinyl chloride receiver layer and polymer containing hollow particles FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-8017551-B2 Multilayer; support, vinyl chloride receiver layer and polymer containing hollow particles FUJIFILM CORPORATION (JP) 2011-09-13 US disclosed
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20070213224-A1 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070213224-A1 Heat-sensitive transfer image-receiving sheet FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242542-A1 INDANILINE DYE, THERMAL TRANSFER RECORDING INK SHEET, THERMAL TRANSFER RECORDING METHOD, COLOR TONER, INKJET INK, AND COLOR FILTER INMT, TYR, IK ALDH1A1 401/4885TSHR 1060/4885MAPT 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.