Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNN2 | Q9H2S1 | 3/20 | 0.30 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.30 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107698 | 0.82 | HTR2C (0.43) | REN | |
| SCHEMBL12110555 | 0.82 | REN (0.41) | RENKDM4ETSHR | |
| SCHEMBL14553894 | 0.81 | USP30 (0.39) | REN | |
| SCHEMBL1293871 | 0.76 | REN (0.45) | RENHTR1ASLC6A4CYP2D6GRM5 | |
| SCHEMBL12107655 | 0.76 | HTR2C (0.44) | — | |
| SCHEMBL12110569 | 0.74 | USP30 (0.40) | TSHR | |
| SCHEMBL12105710 | 0.71 | GPR119 (0.39) | — | |
| SCHEMBL12110145 | 0.70 | CHRM1 (0.35) | MAOAHTR1A | |
| SCHEMBL18055305 | 0.70 | REN (0.42) | RENHTR1ASLC6A4GRM5TSHR | |
| SCHEMBL14641708 | 0.69 | GRM5 (0.41) | RENHTR1ASLC6A4ALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269744-A1 | Benzazepine Compound | ASTELLAS PHARMA INC. (JP) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269744-A1 | Benzazepine Compound | HTR2C, HTR3C, HTR2A | REN 1554/4885MAOA 124/4885HTR1A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.