SCHEMBL12117358

SCHEMBL12117358

COc1cc2c(cc1C)OCCO2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.47
▸ PKM P14618 2/20 0.47
▸ USP2 O75604 1/20 0.47
▸ HPGD P15428 2/20 0.43
▸ LMNA P02545 1/20 0.43
▸ PLK1 P53350 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ TP53 P04637 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ TSHR P16473 2/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ ERN1 O75460 1/20 0.38
▸ P2RX7 Q99572 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL785194 0.87 LMNA (0.56) GAAUSP2HPGDLMNAALDH1A1
SCHEMBL15982610 0.80 EP300 (0.46) GAAHPGDLMNAPLK1SMN1; SMN2
SCHEMBL15982615 0.80 EP300 (0.46) GAAHPGDLMNAPLK1SMN1; SMN2
SCHEMBL15982322 0.80 EP300 (0.46) GAAHPGDLMNAPLK1SMN1; SMN2
SCHEMBL8525889 0.78 ALDH1A1 (0.47) GAAHPGDLMNAALDH1A1SMN1; SMN2
SCHEMBL9110788 0.77 ALDH1A1 (0.51) GAAPKMHPGDLMNAPLK1
SCHEMBL27033010 0.77 MEN1 (0.47) HPGDLMNASMN1; SMN2TP53MAPT
SCHEMBL29828820 0.77 MEN1 (0.47) HPGDLMNASMN1; SMN2TP53MAPT
SCHEMBL12117360 0.77 GAA (0.43) GAAHPGDLMNAPLK1ALDH1A1
SCHEMBL13382355 0.77 DRD2 (0.47) GAAPKMUSP2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 — — US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 GAA 877/4885PKM 4159/4885USP2 3770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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