SCHEMBL12127

SCHEMBL12127

Cc1ccc(F)c(O)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30413683 1.00
SCHEMBL27816817 0.87 TRPA1 (0.46)
SCHEMBL27870665 0.87 TRPA1 (0.46)
SCHEMBL7363869 0.87 ALDH1A1 (0.57)
Metacresol SCHEMBL10549611 0.85 ACHE (0.65)
SCHEMBL27886866 0.84 TRPA1 (0.43)
SCHEMBL27886847 0.82 TRPA1 (0.42)
SCHEMBL23258726 0.81 TRPA1 (0.50)
SCHEMBL130630 0.79
SCHEMBL28119501 0.77 TRPA1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 629 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-118359751-A Polymer microsphere using aromatic compound as stabilizer and preparation method thereof 海南大学 2024-07-19 CN claimed
CN-111836801-B Compounds for inhibiting TNIK and medical use thereof 韩国化学硏究院 2024-02-02 CN claimed
WO-2023183943-A1 PYRIDO-[3,4-D]PYRIDAZINE AMINE DERIVATIVES USEFUL AS NLRP3 DERIVATIVES VENTUS THERAPEUTICS U.S., INC. (US) 2023-09-28 WO claimed
CN-114315528-B Novel method for preparing 4-dimethyl aryl substituted phenol compound by silver catalysis 湖南理工学院 2023-06-27 CN claimed
CN-115557929-A Somatostatin modulators and uses thereof 克林提克斯医药股份有限公司 2023-01-03 CN claimed
CN-114315528-A Novel method for preparing 4-dimethyl aryl substituted phenol compound by silver catalysis 湖南理工学院 2022-04-12 CN claimed
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
EP-4477271-B1 N-(PHENYL)-5-(HETEROARYL)-1H-PYRAZOL-3-AMINE DERIVATIVES AS TNIK INHIBITORS FOR USE IN THE TREATMENT OF CANCER KOREA RES INST CHEMICAL TECH (KR) 2026-05-13 EP disclosed
US-20260021192-A1 PROTEINS HAVING A COVALENT WARHEAD TOPAZ THERAPEUTICS INC (US) 2026-01-22 US disclosed
EP-4680601-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES Sanofi (FR) 2026-01-21 EP disclosed
US-12479844-B2 Ion channel modulators PRAXIS PRECISION MEDICINES, INC. (US) 2025-11-25 US disclosed
US-12421193-B2 GPR52 modulators and methods of use NEUROCRINE BIOSCIENCES, INC. (US) 2025-09-23 US disclosed
CN-1060652-A OXAMIDES SMITHKLINE BEECHAM CORP (US) 1992-04-29 CN disclosed
WO-1992000968-A1 OXAMIDES SMITHKLINE BEECHAM CORPORATION (US) 1992-01-23 WO disclosed
US-4697011-A N-fluoro-N-perfluoromethyl sulfonamides RESEARCH CORPORATION (US) 1987-09-29 US disclosed
EP-0075146-B1 BENZYL ESTERS WITH FLUOROSUBSTITUTED ETHER GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR UTILISATION AS INSECTICIDES BAYER AG (DE) 1985-10-23 EP disclosed
US-4524032-A USING FLUORINE GAS IN AN INERT SOLVENT AND COOLING DAIKIN KOGYO CO., LTD. (JP) 1985-06-18 US disclosed
EP-0075146-A1 Benzyl esters with fluorosubstituted ether groups, process for their preparation and their utilisation as insecticides BAYER AG (DE) 1983-03-30 EP disclosed
US-4087444-A Amides as ovulation inhibitors ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed