Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.38 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 4/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.34 |
| ▸ | MERTK | Q12866 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138811 | 0.86 | GRM5 (0.44) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL12131851 | 0.78 | GRM5 (0.43) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL1723715 | 0.77 | NNMT (0.53) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL8385220 | 0.74 | GRM5 (0.41) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL12131816 | 0.74 | KIF11 (0.52) | AXLTYRO3MERTKGRM4HDAC3 | |
| SCHEMBL13139105 | 0.72 | ADRA2A (0.51) | NNMTGRM5PIK3C3ADRA2AADRA2B | |
| SCHEMBL26441622 | 0.72 | NNMT (0.45) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL26441018 | 0.72 | NNMT (0.45) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL10293323 | 0.72 | ASIC3 (0.62) | NNMTGRM5ASIC3ALOX5APFEN1 | |
| SCHEMBL12960824 | 0.72 | ADRA2A (0.50) | NNMTGRM5ASIC3PIK3C3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110280808-A1 | Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins | AC IMMUNE, S.A. (CH) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280808-A1 | Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins | APP, PSEN1, PSEN2 | NNMT 1618/4885GRM5 1778/4885ASIC3 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.