Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132288 | 0.90 | UCHL3 (0.46) | ADORA3HSD11B1UCHL3RORARORC | |
| SCHEMBL12132283 | 0.88 | ICMT (0.43) | HSD11B1RORARORCRORBNPC1 | |
| SCHEMBL12132282 | 0.87 | RAB9A (0.48) | ADORA3ADORA1NPC1RAB9AATM | |
| SCHEMBL23118981 | 0.83 | PSMB5 (0.40) | ADORA3HSD11B1UCHL3RORARORC | |
| SCHEMBL12132298 | 0.83 | NPC1 (0.46) | RORARORCRORBPSMB5NPC1 | |
| SCHEMBL23118777 | 0.82 | PSMB5 (0.40) | ADORA3HSD11B1UCHL3RORARORC | |
| SCHEMBL12132274 | 0.81 | CASR (0.45) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL24549588 | 0.81 | HSD11B1 (0.39) | ADORA3HSD11B1UCHL3RORARORC | |
| SCHEMBL12132277 | 0.81 | CYP1A1 (0.40) | ADORA3ADORA1NPC1RAB9AATM | |
| SCHEMBL23118774 | 0.80 | HSD11B1 (0.39) | ADORA3HSD11B1UCHL3RORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110284829-A1 | POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |