SCHEMBL12134708

SCHEMBL12134708

CCO[Si](CCCNC(=O)NCCOC(=O)C(C)(C)CC)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.33
TSHR P16473 1/20 0.33
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12134707 0.86 ACHE (0.47) ACHE
SCHEMBL4400245 0.84 CYP4F2 (0.37) CYP4F2CYP4A11
SCHEMBL2561394 0.81 EPHX1 (0.48) EPHX1TSHRACHE
SCHEMBL13948295 0.80 EPHX1 (0.37) EPHX1TSHR
SCHEMBL13216865 0.79 RECQL (0.40) EPHX1TSHR
SCHEMBL4419366 0.79 EPHX1 (0.47) EPHX1TSHRACHE
SCHEMBL13130658 0.78 RIPK1 (0.38) EPHX1ACHE
SCHEMBL21924987 0.78 EPHX1 (0.40) EPHX1TSHR
SCHEMBL4362272 0.77 EPHX1 (0.55) EPHX1
SCHEMBL12134700 0.77 TSHR (0.39) EPHX1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110287244-A1 HYDROPHILIC FILM FUJIFILM CORPORATION (JP) 2011-11-24 US disclosed
US-20110259571-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC MEMBER HAVING ANTIFUNGAL PROPERTY FUJIFILM CORPORATION (JP) 2011-10-27 US disclosed
US-8012591-B2 and a Si, Ti, Zr, or Al alkoxide; antisoiling, antifogging film for antireflection films, optical filters, lenses, lenses and mirrors; acrylamide copolymers FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-20110108262-A1 HYDROPHILIC MEMBER, FIN STOCK, ALUMINUM-MADE FIN STOCK, HEAT EXCHANGER AND AIR CONDITIONER FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-20100293994-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC MEMBER HAVING ANTIFUNGAL PROPERTY FUJIFILM CORPORATION (JP) 2010-11-25 US disclosed
US-20100200207-A1 HYDROPHILIC COMPOSITION FUJIFILM CORPORATION (JP) 2010-08-12 US disclosed
US-20100196724-A1 HYDROPHILIC FILM FORMING COMPOSITION AND HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2010-08-05 US disclosed
US-20100159256-A1 COMPOSITION FOR FORMING HYDROPHIC FIRM, SPRAY COMPOSITION AND HYDROPHILIC MEMBER USING THE SAME FUJIFILM CORPORATION (JP) 2010-06-24 US disclosed
US-20090239051-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC TREATED MEMBER FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-20080241557-A1 HYDROPHILIC MEMBER AND UNDERCOATING COMPOSITION FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080176085-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080102286-A1 HYDROPHILIC MEMBER AND SUBSTRATE FOR HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100293994-A1 HYDROPHILIC COMPOSITION AND HYDROPHILIC MEMBER HAVING ANTIFUNGAL PROPERTY ERG28, HSPH1, HDHD5 EPHX1 1857/4885TSHR 4852/4885CYP4F2 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.