SCHEMBL12141900

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13693067	0.81	HSD11B1 (0.46)	HSD11B1TDP1HRH4ALDH1A1POLB
	SCHEMBL14868480	0.80	SMN1; SMN2 (0.51)	ALDH1A1HRH3HPGDSMN1; SMN2NPC1
	SCHEMBL12775348	0.78	ALDH1A1 (0.43)	HSD11B1TDP1HRH4ALDH1A1POLB
	SCHEMBL23733490	0.77	HRH3 (0.52)	ALDH1A1HRH3POLBMEN1KMT2A
	SCHEMBL25709612	0.72	HRH3 (0.48)	ALDH1A1HRH3POLBMEN1KMT2A
	SCHEMBL12545322	0.71	ALDH1A1 (0.72)	ALDH1A1HRH3POLBMEN1KMT2A
	SCHEMBL2378438	0.70	CYP1A2 (0.50)	HSD11B1TDP1HRH4ALDH1A1HRH3
	SCHEMBL30917885	0.70	TDP1 (0.50)	HSD11B1TDP1HRH3SMN1; SMN2KDM4E
	SCHEMBL20353604	0.70	L3MBTL1 (0.76)	HSD11B1HRH4ALDH1A1SMN1; SMN2
	SCHEMBL23742742	0.70	CYP2D6 (0.57)	ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.