Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445212 | 0.83 | KDM4E (0.51) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL9853394 | 0.75 | ADORA2B (0.45) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL14629809 | 0.75 | SMN1; SMN2 (0.51) | PDE4AADORA2APDE4DADORA2BADORA3 | |
| SCHEMBL15075374 | 0.74 | ALOX15 (0.49) | ADORA2AMAPK1ALOX15ADORA1 | |
| SCHEMBL9287679 | 0.70 | ADORA2A (0.53) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL6944694 | 0.70 | SMN1; SMN2 (0.56) | MEN1KMT2AMAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL10650075 | 0.69 | MEN1 (0.35) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL2547503 | 0.69 | ADORA2B (0.41) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL9844553 | 0.69 | PDE4A (0.56) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL5867203 | 0.69 | TSHR (0.48) | MEN1KMT2AMAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142381-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | FUJITA TAKASHI (JP) | 2011-11-17 | — | — | WO | disclosed |