Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.32 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355359 | 0.83 | SMN1; SMN2 (0.38) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6358200 | 0.82 | CYP1A2 (0.46) | TSHRKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20934157 | 0.82 | SMN1; SMN2 (0.39) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL4701760 | 0.81 | MAPT (0.42) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL14038091 | 0.81 | LMNA (0.34) | KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18916495 | 0.81 | TDP1 (0.39) | MAPTCYP3A4TSHRTDP1KMT2A | |
| SCHEMBL491526 | 0.80 | MAPT (0.53) | MAPTCYP3A4TSHRATMTDP1 | |
| SCHEMBL22777675 | 0.80 | SMN1; SMN2 (0.36) | TSHRKMT2ASMN1; SMN2LMNA | |
| SCHEMBL34383 | 0.80 | SMN1; SMN2 (0.36) | TSHRKMT2ASMN1; SMN2LMNA | |
| SCHEMBL9978168 | 0.80 | MAPK1 (0.44) | MAPTKMT2ASMN1; SMN2ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034981-B2 | Modified bio-related substance, process for producing the same, and intermediate | NOF CORPORATION (JP) | 2011-10-11 | — | — | US | disclosed |
| US-8003117-B2 | Purity; polyether containing glycerol backbone capable of being label | NOF CORPORATION (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20110082277-A1 | MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE | NOF CORPORATION (JP) | 2011-04-07 | — | — | US | disclosed |
| US-7851491-B2 | Modified bio-related substance, process for producing the same, and intermediate | NOF CORPORATION (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20090192320-A1 | MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE | NOF CORPORATION (JP) | 2009-07-30 | — | — | US | disclosed |
| US-7524875-B2 | Modified bio-related substance, process for producing the same, and intermediate | NOF CORPORATION (JP) | 2009-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192320-A1 | MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE | BMP1, BMP2, AQP1 | MAPT 4041/4885CYP3A4 1170/4885TSHR 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.