Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | TST | Q16762 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698290 | 0.92 | MAPT (0.35) | MAPTLMNATDP1ALDH1A1CYP3A4 | |
| SCHEMBL4698289 | 0.86 | ALDH1A1 (0.35) | LMNATDP1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL3101630 | 0.83 | DGKA (0.49) | MAPTALDH1A1KMT2ASMN1; SMN2PRKCA | |
| SCHEMBL16075079 | 0.83 | ALDH1A1 (0.64) | LMNAALDH1A1SMN1; SMN2PRKCAPRKCE | |
| SCHEMBL917125 | 0.82 | MEN1 (0.36) | LMNATDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL12201703 | 0.81 | MAPT (0.38) | MAPTLMNATDP1ALDH1A1CYP3A4 | |
| SCHEMBL2193456 | 0.80 | MEN1 (0.35) | LMNATDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL4699686 | 0.80 | TDP1 (0.35) | LMNATDP1CYP3A4KMT2AMEN1 | |
| SCHEMBL3459097 | 0.80 | DGKA (0.56) | MAPTLMNAALDH1A1TSHRKMT2A | |
| SCHEMBL12972246 | 0.79 | KMT2A (0.35) | LMNATDP1CYP3A4ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |