Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437106 | 0.79 | TDP1 (0.48) | CYP2C19NR1D1LMNAALOX15TSHR | |
| SCHEMBL13332454 | 0.76 | ALDH1A1 (0.43) | CYP2C19MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL23130693 | 0.76 | AKT1 (0.50) | CYP2C19MEN1CYP3A4KMT2AAKT1 | |
| SCHEMBL8018235 | 0.76 | AKT1 (0.50) | CYP2C19MEN1CYP3A4KMT2AAKT1 | |
| SCHEMBL7570965 | 0.76 | AKT1 (0.50) | CYP2C19MEN1CYP3A4KMT2AAKT1 | |
| SCHEMBL13603880 | 0.76 | TDP1 (0.41) | CYP2C19MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL7562431 | 0.75 | AKT1 (0.49) | CYP2C19MEN1CYP3A4KMT2AAKT1 | |
| SCHEMBL16087987 | 0.74 | NR1D1 (0.32) | NR1D1NR1H3 | |
| SCHEMBL28184171 | 0.74 | GSTO1 (0.44) | CYP2C19MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL30915258 | 0.73 | AKT1 (0.50) | CYP2C19MEN1CYP3A4KMT2AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8540966-B2 | Contrast agents endowed with high relaxivity | BRACCO IMAGING S.P.A. (IT) | 2013-09-24 | — | — | US | disclosed |
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | BRACCO IMAGING SPA (IT) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256067-A1 | Contrast agents endowed with high relaxivity | SLC40A1, SLC67A1, SLC19A1 | CYP2C19 4045/4885MEN1 435/4885CYP3A4 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.