Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12978498 | 0.92 | LMNA (0.45) | LMNACYP2D6TSHRADRB2ADRB1 | |
| SCHEMBL12222349 | 0.86 | ADRB2 (0.46) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12222360 | 0.86 | LMNA (0.53) | LMNACYP2D6TSHRADRB2ADRB1 | |
| SCHEMBL12222345 | 0.82 | MEN1 (0.43) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12172005 | 0.79 | LMNA (0.43) | LMNA | |
| SCHEMBL4199108 | 0.78 | LMNA (0.62) | LMNACYP2D6TSHRADRB2ADRB1 | |
| SCHEMBL14904490 | 0.77 | LMNA (0.50) | LMNACYP2D6TSHRADRB2ADRB1 | |
| SCHEMBL27250603 | 0.77 | PLA2G4B (0.42) | LMNATSHR | |
| SCHEMBL23074712 | 0.76 | KDM4E (0.60) | LMNATSHRMAPK1L3MBTL1KDM4E | |
| SCHEMBL20905164 | 0.75 | POLB (0.41) | LMNACYP2D6TSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367762-B2 | Compositions comprising glycidyl ether copolymers | BYK-CHEMIE GMBH (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20110257326-A1 | COMPOSITIONS COMPRISING GLYCIDYL ETHER COPOLYMERS | BYK-CHEMIE GMBH (DE) | 2011-10-20 | — | — | US | disclosed |