Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12222347 | 0.92 | LMNA (0.43) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12222349 | 0.91 | ADRB2 (0.46) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12222360 | 0.88 | LMNA (0.53) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL12172005 | 0.87 | LMNA (0.43) | LMNA | |
| SCHEMBL27250603 | 0.84 | PLA2G4B (0.42) | LMNATSHRPLA2G4B | |
| SCHEMBL20905164 | 0.82 | POLB (0.41) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL27250604 | 0.82 | TSHR (0.38) | LMNACYP2D6CYP3A4KDM4ETSHR | |
| SCHEMBL27254126 | 0.80 | LMNA (0.48) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL4199108 | 0.80 | LMNA (0.62) | LMNACYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL19564431 | 0.80 | LPAR5 (0.36) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748542-B2 | Colorant compatible hydrophobically modified polyurethane thickener for paint | HERCULES INCORPORATED (US) | 2014-06-10 | — | — | US | disclosed |
| US-20100324177-A1 | COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYETHYLENEGLYCOL THICKENER FOR PAINT | ISP INVESTMENTS INC. | 2010-12-23 | — | — | US | disclosed |
| US-20090253832-A1 | COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYURETHANE THICKENER FOR PAINT | AVOCA LLC | 2009-10-08 | — | — | US | disclosed |
| US-7550542-B2 | Colorant compatible synthetic thickener for paint | HERCULES INCORPORATED (US) | 2009-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324177-A1 | COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYETHYLENEGLYCOL THICKENER FOR PAINT | LCT, CSGALNACT1, COLGALT1 | LMNA 769/4885CYP2D6 3425/4885ADRB2 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.