Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989635 | 0.84 | ALDH1A1 (0.37) | TRPV4ALDH1A1TDP1CHRNB2CHRNA4 | |
| SCHEMBL9104744 | 0.81 | SCN9A (0.46) | TRPV4ALDH1A1CHRNB2CHRNA4MRGPRX4 | |
| Hydrochloric Acid SCHEMBL28558707 | 0.79 | TRPV4 (0.52) | TRPV4TRPV1DAOKDM1AMAOA | |
| SCHEMBL29417132 | 0.79 | TRPV4 (0.52) | TRPV4ALDH1A1TRPV1DAOPIK3CA | |
| SCHEMBL7992493 | 0.79 | TRPV4 (0.52) | TRPV4TRPV1DAODHFRKDM1A | |
| SCHEMBL3686975 | 0.79 | TRPV4 (0.52) | TRPV4TRPV1DAOKDM1AMAOA | |
| SCHEMBL1474453 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TRPV1TDP1CHRNB2CHRNA4 | |
| SCHEMBL336320 | 0.79 | TRPV4 (0.52) | TRPV4ALDH1A1TRPV1DAOPIK3CA | |
| SCHEMBL31279089 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TRPV1TDP1CHRNB2CHRNA4 | |
| SCHEMBL3851697 | 0.78 | TRPV4 (0.50) | TRPV4TRPV1DAOKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12162840-B2 | Herbicidal compositions | SYNGENTA CROP PROTECTION AG (CH) | 2024-12-10 | — | — | US | disclosed |
| EP-3890487-B1 | HERBICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-06-12 | — | — | EP | disclosed |
| CN-113271779-B | Herbicidal composition | 先正达参股股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-3737667-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-04-03 | — | — | EP | disclosed |
| CN-111566094-B | herbicidal compounds | 先正达参股股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-28 | — | — | US | disclosed |
| EP-4195929-A1 | HERBICIDAL COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-116157016-A | Herbicidal composition | 先正达农作物保护股份公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20220119353-A1 | Herbicidal Compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-21 | — | — | US | disclosed |
| CN-114126597-A | Fibroblast activation protein inhibitor | 普拉西斯生物技术有限责任公司 | 2022-03-01 | — | — | CN | disclosed |
| WO-2010036998-A2 | INDOLE AND INDOLINE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-04-01 | — | — | WO | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| WO-2009120717-A2 | PYRIDO [3, 4-B] INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009120717-A2 | PYRIDO [3, 4-B] INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| WO-2009120720-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES,INC. (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20090239854-A1 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. | 2009-09-24 | — | — | US | disclosed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009055828-A1 | NEW TETRACYCLIC COMPOUNDS | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162840-B2 | Herbicidal compositions | DDT, HPD, PNPO | TRPV4 4489/4885ALDH1A1 284/4885TRPV1 3994/4885 |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | TRPV4 669/4885ALDH1A1 1514/4885TRPV1 482/4885 |
| US-20230301300-A1 | HERBICIDAL COMPOSITIONS | GMDS, DDT, AADAC | TRPV4 4578/4885ALDH1A1 431/4885TRPV1 3716/4885 |
| US-20220119353-A1 | Herbicidal Compositions | DDT, HPD, PNPO | TRPV4 4489/4885ALDH1A1 284/4885TRPV1 3994/4885 |
| US-20090239854-A1 | Tetracyclic compounds | HTR2C, HTR3D, HTR5A | TRPV4 242/4885ALDH1A1 1557/4885TRPV1 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.