Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13660321 | 0.87 | HRH3 (0.60) | GPR119ADRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL1005823 | 0.86 | ALDH1A1 (0.53) | ADRB2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1004178 | 0.86 | GPR119 (0.46) | GPR119ADRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL5205491 | 0.84 | HRH3 (0.60) | GPR119ADRB2MEN1KMT2AHRH3 | |
| SCHEMBL3587239 | 0.84 | GPR119 (0.58) | GPR119ADRB2MEN1KMT2AHRH3 | |
| SCHEMBL3583221 | 0.82 | ADRB2 (0.58) | ADRB2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22533161 | 0.81 | GPR119 (0.61) | GPR119ALDH1A1HRH3 | |
| SCHEMBL3347332 | 0.81 | GPR119 (0.65) | GPR119HRH3 | |
| SCHEMBL23373231 | 0.80 | GPR119 (0.63) | GPR119ADRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL12239155 | 0.80 | HRH3 (0.55) | ADRB2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | GPR119 1/4885ADRB2 131/4885MEN1 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.