Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005982 | 0.85 | GPR119 (0.53) | GPR119ACACB | |
| SCHEMBL2729387 | 0.83 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL12239176 | 0.83 | CSNK2A1 (0.45) | GPR119 | |
| SCHEMBL2730262 | 0.83 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL3693180 | 0.83 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL3696824 | 0.83 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL8515468 | 0.80 | GPR119 (0.53) | GPR119ACACB | |
| SCHEMBL3342687 | 0.78 | GPR119 (0.52) | GPR119ACACBADRB2MEN1KMT2A | |
| SCHEMBL8513552 | 0.78 | GPR119 (0.51) | GPR119ACACB | |
| SCHEMBL3341593 | 0.77 | GPR119 (0.51) | GPR119ACACBADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | GPR119 1/4885ACACB 1480/4885LTA4H 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.