Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 13/20 | 0.39 |
| ▸ | FPR2 | P25090 | 12/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006391 | 0.89 | GPR119 (0.43) | PROKR1FPR2MMP13 | |
| SCHEMBL1006762 | 0.80 | GPR119 (0.45) | PROKR1FPR2MMP13SMN1; SMN2 | |
| SCHEMBL1006266 | 0.78 | GPR119 (0.43) | — | |
| SCHEMBL1006506 | 0.76 | GPR119 (0.47) | PROKR1FPR2NPC1 | |
| SCHEMBL1005491 | 0.71 | GPR119 (0.38) | — | |
| SCHEMBL1005839 | 0.71 | GPR119 (0.44) | — | |
| SCHEMBL1006510 | 0.71 | GPR119 (0.41) | PROKR1FPR2 | |
| SCHEMBL12239176 | 0.69 | CSNK2A1 (0.45) | PROKR1FPR2 | |
| SCHEMBL1003961 | 0.69 | GPR119 (0.41) | SMN1; SMN2NPC1 | |
| SCHEMBL1005451 | 0.68 | PDE4D (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | PROKR1 370/4885FPR2 400/4885MMP13 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.