Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 4/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | SHBG | P04278 | 2/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 1/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MGAM | O43451 | 1/20 | 0.70 |
| ▸ | GABRP | O00591 | 4/20 | 0.63 |
| ▸ | GABRD | O14764 | 4/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.63 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18373741 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL13487248 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL19156379 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL14007476 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL37778 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL23699767 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL17776486 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL12646116 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL675417 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG | |
| SCHEMBL13988206 | 1.00 | AKR1B10 (1.00) | AKR1B10AKR1B1GPBAR1CYP3A4SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322844-A1 | PROCESS FOR PREPARING (3alpha,5alpha)-3-HYDROXY-3-METHYL-PREGNAN-20-ONE (GANAXOLONE) | INDUSTRIALE CHIMICA S.R.L. (IT) | 2023-10-12 | — | — | US | disclosed |
| US-20230322844-A1 | PROCESS FOR PREPARING (3alpha,5alpha)-3-HYDROXY-3-METHYL-PREGNAN-20-ONE (GANAXOLONE) | INDUSTRIALE CHIMICA S.R.L. (IT) | 2023-10-12 | — | — | US | disclosed |
| WO-2022053937-A1 | PROCESS FOR PREPARING (3α,5α)-3-HYDROX Y -3-METHYL-PREGNAN -20- ONE (GANAXOLONE) | INDUSTRIALE CHIMICA S.R.L. (IT) | 2022-03-17 | — | — | WO | disclosed |
| WO-2020006596-A1 | NEUROACTIVE STEROIDS AND METHODS OF PREPARATION | DRAWBRIDGE PHARMACEUTICALS PTY LTD (AU) | 2020-01-09 | — | — | WO | disclosed |
| US-20110263553-A1 | STEROID ANALOGUES FOR NEUROPROTECTION | EMORY UNIVERISITY | 2011-10-27 | — | — | US | disclosed |
| US-20110263553-A1 | STEROID ANALOGUES FOR NEUROPROTECTION | EMORY UNIVERISITY | 2011-10-27 | — | — | US | disclosed |
| WO-2011067501-A1 | LOCAL TOPICAL APPLICATION AMINOSTEROID COMPOUNDS FOR MUCOUS/CUTANEOUS DECOLONIZATION OF STAPHYLOCOCCUS AUREUS | ASSISTANCE PUBLIQUE - HOPITAUX DE MARSEILLE (FR) | 2011-06-09 | — | — | WO | disclosed |
| US-20090118248-A1 | 3-Alpha-hydroxy 21-n-heteroaryl-pregnane derivatives for modulation of brain excitability and a process for the production thereof | EURO-CELTIQUE S.A. (LU) | 2009-05-07 | — | — | US | disclosed |
| US-20090118248-A1 | 3-Alpha-hydroxy 21-n-heteroaryl-pregnane derivatives for modulation of brain excitability and a process for the production thereof | EURO-CELTIQUE S.A. (LU) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263553-A1 | STEROID ANALOGUES FOR NEUROPROTECTION | CYP11A1, NR3C2, HSD17B7 | AKR1B10 283/4885AKR1B1 285/4885GPBAR1 823/4885 |
| US-20090118248-A1 | 3-Alpha-hydroxy 21-n-heteroaryl-pregnane derivatives for modulation of brain excitability and a process for the production thereof | HSD3B1, HSD3B2, CYP17A1 | AKR1B10 414/4885AKR1B1 300/4885GPBAR1 236/4885 |
| US-20230322844-A1 | PROCESS FOR PREPARING (3alpha,5alpha)-3-HYDROXY-3-METHYL-PREGNAN-20-ONE (GANAXOLONE) | CYP17A1, CYP21A2, CYP4A11 | AKR1B10 110/4885AKR1B1 149/4885GPBAR1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.