SCHEMBL12244458

SCHEMBL12244458

Cc1cc(O)cc(Cc2cc(O)cc(CNc3nc(C)nc(N)n3)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.37
CSNK1D P48730 1/20 0.36
CRHR1 P34998 1/20 0.34
ALPL P05186 1/20 0.34
ALPG P10696 1/20 0.34
PLAA Q9Y263 1/20 0.34
EGFR P00533 1/20 0.34
KDR P35968 1/20 0.34
TPH1 P17752 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HTR1A P08908 1/20 0.33
GPR68 Q15743 1/20 0.33
APP P05067 1/20 0.33
HRH4 Q9H3N8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12245487 0.77 GAA (0.49) GAACSNK1DNPSR1HTR1AGPR68
SCHEMBL30899188 0.71 ALDH1A1 (0.60)
SCHEMBL29215628 0.71 ALDH1A1 (0.60)
SCHEMBL14869439 0.69 GAA (0.71) GAANPSR1HTR1AGPR68APP
SCHEMBL12038136 0.66 HSP90AA1 (0.38) GAANPSR1CA1CA2CA9
SCHEMBL15100791 0.65 PIM1 (0.45) GAANPSR1CA1CA2CA9
SCHEMBL7770137 0.64 LMNA (0.45) GAA
SCHEMBL14869316 0.64 ALPL (0.50) GAAALPLALPGPLAANPSR1
SCHEMBL10483510 0.64 MEN1 (0.63) GAA
SCHEMBL6838173 0.64 CA9 (0.60) GAACSNK1DNPSR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110253434-A1 EPOXY RESIN COMPOSITION, AND PREPREG AND PRINTED CIRCUIT BOARD USING THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2011-10-20 US disclosed