SCHEMBL1225396

SCHEMBL1225396

CO[Si](Cl)(CC1CO1)OC

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225465 0.81
SCHEMBL1224348 0.77 ALDH1A1 (0.33) ALDH1A1TDP1SMN1; SMN2
SCHEMBL198113 0.75 ALDH1A1 (0.36) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2
SCHEMBL203335 0.75 ALDH1A1 (0.36) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2
SCHEMBL27731585 0.75 ALDH1A1 (0.36) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2
SCHEMBL637425 0.75 ALDH1A1 (0.36) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2
SCHEMBL3068447 0.75
SCHEMBL3848487 0.74
Cyclopropane SCHEMBL3461994 0.71 ALDH1A1 (0.33) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2
SCHEMBL662055 0.71 ALDH1A1 (0.33) ALDH1A1TDP1TSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961610-B Pressure-sensitive adhesive composition, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet 琳得科株式会社 2023-07-18 CN disclosed
CN-112961610-A Pressure-sensitive adhesive composition, pressure-sensitive adhesive, and pressure-sensitive adhesive sheet 琳得科株式会社 2021-06-15 CN disclosed
CN-104212409-B The main binding agent being made up of polyorganosiloxane compounds 琳得科株式会社 2016-08-24 CN disclosed
CN-101965387-B Adhesive agent mainly composed of polyorganosiloxane compound LINTEC CORP 2015-01-07 CN disclosed
CN-104232016-A Adhesive mainly composed of polyorganosiloxane compound LINTEC CORP 2014-12-24 CN disclosed
CN-104212409-A Adhesive mainly composed of polyorganosiloxane compound LINTEC CORP 2014-12-17 CN disclosed
US-8728624-B2 Fixing material comprising silane compound polymer and photonic device sealed body LINTEC CORPORATION (JP) 2014-05-20 US disclosed
US-8507044-B2 Molding material composed of polyorganosiloxane compound, sealing material, and sealed optical device LINTEC CORPORATION (JP) 2013-08-13 US disclosed
US-8481669-B2 Molding material comprising polysilsesquioxane compound, sealing material, and sealed optical element LINTEC CORPORATION (JP) 2013-07-09 US disclosed
US-8470953-B2 Sealing material for optical element and sealed optical element LINTEC CORPORATION (JP) 2013-06-25 US disclosed
US-20130096253-A1 FIXING MATERIAL COMPRISING SILANE COMPOUND POLYMER AND PHOTONIC DEVICE SEALED BODY LINTEC CORPORATION (JP) 2013-04-18 US disclosed
US-8357261-B2 Adhesive mainly composed of polyorganosiloxane compound LINTEC CORPORATION (JP) 2013-01-22 US disclosed
US-20110288257-A1 SEALING MATERIAL FOR OPTICAL ELEMENT AND SEALED OPTICAL ELEMENT KASHIO MIKIHIRO (JP) 2011-11-24 US disclosed
US-8026332-B2 curable seals for optics comprising polysilsesquioxanes with a ladder structure, having excellent transparency, crack and heat resistance LINTEC CORPORATION (JP) 2011-09-27 US disclosed
US-20110124812-A1 FIXING MATERIAL COMPRISING SILANE COMPOUND POLYMER AND PHOTONIC DEVICE SEALED BODY LINTEC CORPORATION (JP) 2011-05-26 US disclosed
US-20110054139-A1 ADHESIVE MAINLY COMPOSED OF POLYORGANOSILOXANE COMPOUND LINTEC CORPORATION (JP) 2011-03-03 US disclosed
US-20110034659-A1 MOLDING MATERIAL COMPOSED OF POLYORGANOSILOXANE COMPOUND, SEALING MATERIAL, AND SEALED OPTICAL DEVICE LINTEC CORPORATION (JP) 2011-02-10 US disclosed
CN-101965387-A Adhesive agent mainly composed of polyorganosiloxane compound LINTEC CORP 2011-02-02 CN disclosed
US-20090005530-A1 Molding material comprising polysilsesquioxane compound, sealing material, and sealed optical element LINTEC CORPORATION (JP) 2009-01-01 US disclosed
US-20080249278-A1 Sealing material for optical element and sealed optical element LINTEC CORPORATION (JP) 2008-10-09 US disclosed