SCHEMBL12260643

SCHEMBL12260643

Bc1ccc(Cc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ CALM1 P0DP23 1/20 0.67
▸ LTA4H P09960 2/20 0.50
▸ IDH1 O75874 1/20 0.48
▸ PLA2G10 O15496 1/20 0.46
▸ PLA2G2A P14555 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ SLC22A2 O15244 1/20 0.45
▸ CA12 O43570 1/20 0.42
▸ CA1 P00915 1/20 0.42
▸ CA2 P00918 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ CA14 Q9ULX7 1/20 0.42
▸ PPARG P37231 3/20 0.41
▸ PPARA Q07869 3/20 0.41
▸ BCL2 P10415 1/20 0.41
▸ BCL2L1 Q07817 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ HNF4A P41235 1/20 0.41
▸ EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13227358 0.88 ALDH1A1 (0.47) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL972712 0.85 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL8094422 0.85 CALM1 (0.92) CALM1LTA4HIDH1PLA2G10PLA2G2A
Hydrochloric Acid SCHEMBL27978245 0.82 CALM1 (0.86) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL14763944 0.82 CALM1 (1.00) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL1303 0.82 CALM1 (1.00) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL4361124 0.82 CALM1 (1.00) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL3792579 0.82 CALM1 (1.00) CALM1LTA4HIDH1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL28172316 0.82 CALM1 (1.00) CALM1LTA4HIDH1PLA2G10PLA2G2A
SCHEMBL12260623 0.79 HTR2A (0.60) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020043087-A1 METHOD OF DETECTING HUMAN SERUM ALBUMIN IN BIOLOGICAL FLUIDS THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2020-03-05 — — WO disclosed
US-20150344503-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE, METHODS OF TREATMENT AND METHODS OF PREPARING SAME INFINITY PHARMACEUTICALS INC (US) 2015-12-03 — — US disclosed
US-9108989-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2015-08-18 — — US disclosed
US-20140121183-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2014-05-01 — — US disclosed
US-8629125-B2 Inhibitors of fatty acid amide hydrolase Infinty Pharmaceuticals, Inc. (US) 2014-01-14 — — US disclosed
US-20130059819-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed
US-8349814-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2013-01-08 — — US disclosed
US-8329675-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2012-12-11 — — US disclosed
US-20110230440-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE ADAMS JULIAN 2011-09-22 — — US disclosed
US-20110224171-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. 2011-09-15 — — US disclosed
US-7947663-B2 Inhibitors of fatty acid amide hydrolase INFINITY PHARMACEUTICALS, INC. (US) 2011-05-24 — — US disclosed
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE INFINITY DISCOVERY, INC. (US) 2009-04-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224171-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CALM1 2950/4885LTA4H 6/4885IDH1 2563/4885
US-20090099131-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CALM1 2950/4885LTA4H 6/4885IDH1 2563/4885
US-20150344503-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE, METHODS OF TREATMENT AND METHODS OF PREPARING SAME FAAH, FAAH2, ASAH1 CALM1 3011/4885LTA4H 7/4885IDH1 2286/4885
US-20140121183-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CALM1 2950/4885LTA4H 6/4885IDH1 2563/4885
US-20110230440-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CALM1 2950/4885LTA4H 6/4885IDH1 2563/4885
US-20130059819-A1 INHIBITORS OF FATTY ACID AMIDE HYDROLASE FAAH, FAAH2, ASAH1 CALM1 2950/4885LTA4H 6/4885IDH1 2563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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