Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.42 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13476024 | 0.86 | LTA4H (0.49) | LTA4HLYPLA1LYPLA2L3MBTL1KDM4E | |
| SCHEMBL12270720 | 0.82 | LYPLA1 (0.49) | LTA4HLYPLA1LYPLA2L3MBTL1KDM4E | |
| SCHEMBL12266297 | 0.82 | LYPLA1 (0.65) | LTA4HLYPLA1LYPLA2KDM4EALDH1A1 | |
| SCHEMBL18782421 | 0.81 | KDM4E (0.57) | LYPLA1LYPLA2L3MBTL1KDM4EHTR1B | |
| SCHEMBL12266342 | 0.81 | LYPLA1 (0.50) | LTA4HLYPLA1LYPLA2L3MBTL1HTR1B | |
| SCHEMBL12271034 | 0.80 | LYPLA1 (0.48) | LYPLA1LYPLA2L3MBTL1KDM4EHTR1B | |
| SCHEMBL16151505 | 0.80 | KDM4E (0.55) | LTA4HLYPLA1LYPLA2KDM4EALDH1A1 | |
| SCHEMBL12266290 | 0.77 | CYP1A2 (0.49) | LYPLA1LYPLA2L3MBTL1KDM4EHTR1B | |
| SCHEMBL13383648 | 0.77 | DRD4 (0.46) | LYPLA1LYPLA2KDM4EALDH1A1MEN1 | |
| SCHEMBL2404635 | 0.77 | HTR1D (0.32) | LYPLA1LYPLA2KDM4EHTR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017809-B2 | Bisboron compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087645-A1 | NOVEL BISBORON COMPOUND | KCNMB4, CA2, NR0B2 | LTA4H 4660/4885LYPLA1 4548/4885LYPLA2 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.