SCHEMBL1228265

SCHEMBL1228265

Nc1ccc2c(c1-c1ccccc1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
HPGD P15428 2/20 0.68
ALOX12 P18054 2/20 0.68
CYP2C9 P11712 1/20 0.68
ALOX15 P16050 1/20 0.68
BRCA1 P38398 1/20 0.68
HSD17B10 Q99714 1/20 0.68
FTO Q9C0B1 10/20 0.57
MAPT P10636 3/20 0.57
MEN1 O00255 2/20 0.57
HTT P42858 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP2C19 P33261 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
SMAD3 P84022 1/20 0.57
PRMT1 Q99873 1/20 0.57
ACE2 Q9BYF1 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1228286 0.88 ALDH1A1 (0.71) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL139173 0.87 FTO (0.65) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL82165 0.85 FTO (0.63) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL29044412 0.84 ALDH1A1 (0.67) ALDH1A1HPGDALOX12CYP2C9ALOX15
Hydrochloric Acid SCHEMBL3791930 0.84 FTO (0.61) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL4452146 0.81 FTO (0.70) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL5431416 0.81 FTO (0.57) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL8658740 0.81 FTO (0.57) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL2332830 0.80 FTO (0.67) ALDH1A1HPGDALOX12CYP2C9ALOX15
SCHEMBL3189664 0.79 FTO (0.66) ALDH1A1HPGDALOX12CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459229-B1 USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENT (C N R S ) (FR) 2018-02-28 EP claimed
US-9061069-B2 Use of constrained peptide mimic oligomers as vectorization agents CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-06-23 US claimed
US-6335205-B1 Method and test strip for determining an analyte ROCHE DIAGNOSTICS GMBH (DE) 2002-01-01 US claimed
WO-2023213499-A9 BACTERIAL MYELOPEROXIDASE-CATALASE AND APPLICATIONS THEREOF Universite de Bordeaux (FR) 2023-12-28 WO disclosed
WO-2023213499-A1 BACTERIAL MYELOPEROXIDASE-CATALASE AND APPLICATIONS THEREOF Universite de Bordeaux (FR) 2023-11-09 WO disclosed
CN-115671083-A Composition for inhibiting nerve cell degeneration 株式会社佐藤园 2023-02-03 CN disclosed
US-11299590-B2 Process for preparation of bioorganic nylon polymers and their use as antibacterial material UNIVERSITE DE MONTPELLIER 2022-04-12 US disclosed
CN-112940266-B Ultra-small nano metal organic framework material and preparation method thereof 浙江大学 2022-01-28 CN disclosed
CN-108495882-B Preparation method of bio-organic nylon polymer and application of bio-organic nylon polymer as antibacterial material 蒙彼利埃大学 2021-11-16 CN disclosed
CN-112940266-A Ultra-small nano metal organic framework material and preparation method thereof 浙江大学 2021-06-11 CN disclosed
US-20210115071-A1 NANOSCALE METAL-ORGANIC FRAMEWORKS FOR ENHANCED TUMOR CHEMORADIATION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-04-22 US disclosed
US-20110251404-A1 REAGENT FOR MEASUREMENT OF ACTIVE OXYGEN THE UNIVERSITY OF TOKYO (JP) 2011-10-13 US disclosed
WO-2011012729-A1 USE OF CONSTRAINED DIPEPTIDE AND TRIPEPTIDE MIMIC OLIGOMERS AS VECTORIZATION AGENTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-02-03 WO disclosed
WO-2010021512-A2 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 WO disclosed
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 US disclosed
US-20090155316-A1 Oral Wash APT CO., LTD. (JP) 2009-06-18 US disclosed
EP-1842524-A1 CLEANING LIQUID FOR ORAL CAVITY APT Co., Ltd. (JP) 2007-10-10 EP disclosed
WO-2007088446-A2 A PROCESS AND A REAGENT KIT FOR THE EXAMINATION OF THE METABOLIC STATE RELATED TO THE CARBOHYDRATE AND LIPID METABOLISM OF A HUMAN ORGANISM N-GENE RESEARCH LABORATORIES INC. (US) 2007-08-09 WO disclosed
US-20060025335-A1 Netrin compositions and methods of using the same NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-02-02 US disclosed
WO-2005074556-A2 NETRIN COMPOSITIONS AND METHODS OF USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2005-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251404-A1 REAGENT FOR MEASUREMENT OF ACTIVE OXYGEN CBR1, CBR3, HAO2 ALDH1A1 321/4885HPGD 20/4885ALOX12 396/4885
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES NOXO1, NOX3, SOS1 ALDH1A1 1247/4885HPGD 3258/4885ALOX12 667/4885
US-11299590-B2 Process for preparation of bioorganic nylon polymers and their use as antibacterial material DDC, PDCD2L, PCBP1 ALDH1A1 4753/4885HPGD 4010/4885ALOX12 3791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.