Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 8/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.69 |
| ▸ | ADRA1B | P35368 | 8/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.69 |
| ▸ | HTR1A | P08908 | 2/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067271 | 1.00 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13633242 | 0.86 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL51245 | 0.84 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL9548034 | 0.84 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL14388991 | 0.84 | ADRA1A (0.56) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13985899 | 0.84 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL11218388 | 0.84 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL9548113 | 0.84 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL12225350 | 0.84 | ADRA1A (0.57) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL3169158 | 0.83 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222452-B2 | Method for producing optically active amines | HAMARI CHEMICALS, LTD. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | HAMARI CHEMICALS, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20090137844-A1 | Crystallization process | FERMION OY (FI) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137844-A1 | Crystallization process | KLK5, REN, PCSK6 | ADRA1D 76/4885ADRA1A 65/4885ADRA1B 75/4885 |
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | INMT, HNMT, PADI3 | ADRA1D 1633/4885ADRA1A 1737/4885ADRA1B 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.