Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
| ▸ | TAF1 | P21675 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12127598 | 0.86 | MTNR1A (0.31) | — | |
| SCHEMBL12131846 | 0.79 | HTR6 (0.36) | — | |
| SCHEMBL12128639 | 0.75 | APP (0.40) | — | |
| SCHEMBL12285819 | 0.75 | PADI4 (0.32) | — | |
| SCHEMBL21088076 | 0.74 | ALOX5 (0.42) | MCHR1 | |
| SCHEMBL12127646 | 0.73 | HTR6 (0.31) | — | |
| SCHEMBL12128641 | 0.73 | LMNA (0.39) | — | |
| SCHEMBL25846106 | 0.73 | ALOX5 (0.44) | MCHR1 | |
| SCHEMBL12127664 | 0.72 | CD38 (0.33) | — | |
| SCHEMBL12127617 | 0.72 | HTR6 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128455-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH AMYLOID OR AMYLOID-LIKE PROTEINS | AC IMMUNE S.A. (CH) | 2011-10-20 | — | — | WO | disclosed |