Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285666 | 0.77 | RXFP1 (0.73) | KMT2ALMNATP53THRBRXFP1 | |
| SCHEMBL30774061 | 0.75 | L3MBTL1 (0.75) | KMT2ALMNATP53THRBRAB9A | |
| SCHEMBL1895578 | 0.75 | L3MBTL1 (0.75) | KMT2ALMNATP53THRBRAB9A | |
| SCHEMBL12668678 | 0.74 | MAPT (0.57) | KMT2ALMNATP53THRBRAB9A | |
| SCHEMBL470775 | 0.73 | MAPT (0.85) | KMT2ATP53THRBRXFP1ALDH1A1 | |
| SCHEMBL12285491 | 0.72 | RXFP1 (1.00) | TP53THRBRXFP1MAPTPOLB | |
| SCHEMBL19427445 | 0.70 | ALDH1A1 (0.75) | KMT2ALMNARAB9AALDH1A1MEN1 | |
| SCHEMBL12288667 | 0.69 | RXFP1 (0.70) | KMT2ATP53THRBRXFP1ALDH1A1 | |
| SCHEMBL19427444 | 0.69 | ALDH1A1 (0.73) | KMT2ALMNARAB9AALDH1A1MEN1 | |
| SCHEMBL14707901 | 0.68 | MAPT (0.81) | KMT2ALMNATP53THRBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133722-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |