Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289732 | 0.93 | NPSR1 (0.46) | TP53POLBHTTALDH1A1LMNA | |
| SCHEMBL12289580 | 0.83 | KMT2A (0.40) | TP53ALDH1A1LMNAACHEMEN1 | |
| SCHEMBL11026286 | 0.81 | NPSR1 (0.43) | ALDH1A1NPSR1ADORA3GABRPGABRD | |
| SCHEMBL12289615 | 0.76 | NPSR1 (0.46) | TP53HTTALDH1A1LMNAMEN1 | |
| SCHEMBL16938466 | 0.76 | KDM4E (0.43) | ALDH1A1NPSR1ADORA3GABRPGABRD | |
| SCHEMBL11939828 | 0.76 | LTA4H (0.39) | ALDH1A1LMNANPSR1ADORA3GABRP | |
| SCHEMBL11939863 | 0.76 | MAPT (0.45) | TP53HTTALDH1A1LMNAACHE | |
| SCHEMBL12808507 | 0.75 | ADORA3 (0.40) | LMNAACHENPSR1ADORA3KDM4E | |
| SCHEMBL12289547 | 0.74 | LMNA (0.41) | TP53HTTALDH1A1LMNAMEN1 | |
| SCHEMBL11939859 | 0.73 | TP53 (0.39) | TP53POLBALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242538-A1 | PanK Modulators and Methods Using Same | UNIV YALE (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242538-A1 | PanK Modulators and Methods Using Same | UNIV YALE (US) | 2023-08-03 | — | — | US | disclosed |
| WO-2021262786-A1 | PANK MODULATORS AND METHODS USING SAME | YALE UNIVERSITY (US) | 2021-12-30 | — | — | WO | disclosed |
| US-8815875-B2 | Inhibitors of fatty acid binding protein (FABP) | MERCK SHARP & DOHME CORP. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815875-B2 | Inhibitors of fatty acid binding protein (FABP) | MERCK SHARP & DOHME CORP. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | MERCK SHARP & DOHME LLC | 2011-09-29 | — | — | US | disclosed |
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | MERCK SHARP & DOHME LLC | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242538-A1 | PanK Modulators and Methods Using Same | PANK1, PANK2, PANK3 | TP53 2046/4885POLB 1422/4885HTT 655/4885 |
| US-20110237575-A1 | INHIBITORS OF FATTY ACID BINDING PROTEIN (FABP) | FABP4, FABP1, FABP3 | TP53 3851/4885POLB 4629/4885HTT 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.