SCHEMBL1229338

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7656767	0.83	GAA (0.54)	RPA1ALDH1A1GAAKDM4ECYP1A2
	SCHEMBL1229541	0.81	ALDH1A1 (0.41)	RPA1TYMPALDH1A1GAAKDM4E
	SCHEMBL7649039	0.75	PPP1CA (0.51)	RPA1TYMPALDH1A1GAAKDM4E
	SCHEMBL15549972	0.72	PTGES (0.37)	RHEBCYP2C9IDO1
	SCHEMBL15136902	0.69	TYMP (0.46)	TYMPALDH1A1IDO1
	SCHEMBL7656709	0.68	NPC1 (0.48)	ALDH1A1GAAKDM4ECYP1A2CYP2C9
	SCHEMBL7660378	0.67	ALDH1A1 (0.53)	ALDH1A1GAAKDM4EMAPTLMNA
	SCHEMBL20535350	0.66	RHEB (1.00)	RHEBALDH1A1GAAKDM4ECYP1A2
	SCHEMBL24620062	0.65	RHEB (0.49)	RPA1RHEBALDH1A1KDM4EHTT
	SCHEMBL15136761	0.65	PGR (0.39)	TYMPKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.