SCHEMBL12293602

SCHEMBL12293602

CN(C)Cc1ccc2cc(CN(C)C)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.56
ALDH1A1 P00352 2/20 0.50
TSHR P16473 2/20 0.50
PYCR1 P32322 1/20 0.48
TAAR1 Q96RJ0 2/20 0.48
CA2 P00918 1/20 0.47
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
HTR7 P34969 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
NOS1 P29475 4/20 0.43
NOS2 P35228 1/20 0.43
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12293605 0.92 HRH3 (0.54) HRH3ALDH1A1TSHRPYCR1TAAR1
SCHEMBL17447228 0.91 PYCR1 (0.61) HRH3ALDH1A1TSHRPYCR1TAAR1
SCHEMBL6235431 0.87 ALDH1A1 (0.45) HRH3ALDH1A1TSHRPYCR1TAAR1
Hydrochloric Acid SCHEMBL11277683 0.85 HRH3 (0.43) HRH3ALDH1A1TSHRPYCR1TAAR1
SCHEMBL28798280 0.82 HRH3 (0.41) HRH3ALDH1A1TSHRPYCR1TAAR1
SCHEMBL659509 0.80 HRH3 (0.82) HRH3ALDH1A1TSHRTAAR1HTR7
SCHEMBL12295932 0.78 CYP2C9 (0.48) HRH3ALDH1A1TSHRPYCR1TAAR1
SCHEMBL28217034 0.77 HRH3 (0.54) HRH3ALDH1A1TSHRTAAR1CYP1A2
SCHEMBL989636 0.76 ALDH1A1 (0.67) HRH3ALDH1A1TSHRTAAR1HTR7
SCHEMBL12074778 0.75 HRH3 (0.52) HRH3ALDH1A1TSHRTAAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8026514-B2 Diamine derivatives and organic electronic device using the same LG CHEM, LTD. (KR) 2011-09-27 US disclosed
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100187504-A1 DIAMINE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME DDT, AOC1, DDC HRH3 2422/4885ALDH1A1 396/4885TSHR 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.