Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015915 | 0.99 | TSHR (0.31) | TSHR | |
| SCHEMBL2726083 | 0.81 | TSHR (0.39) | TSHR | |
| SCHEMBL3288186 | 0.80 | TSHR (0.36) | TSHR | |
| SCHEMBL28331619 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL2212633 | 0.74 | TSHR (0.50) | TSHR | |
| SCHEMBL33546 | 0.74 | TSHR (0.38) | TSHR | |
| SCHEMBL29180601 | 0.73 | TSHR (0.36) | TSHR | |
| Hydrochloric Acid SCHEMBL21880081 | 0.72 | MAPT (0.46) | TSHR | |
| Hydrochloric Acid SCHEMBL6271618 | 0.72 | THRB (0.37) | TSHR | |
| Ammonia Solution, Strong SCHEMBL27672291 | 0.71 | ALOX15 (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773866-B1 | USE OF METAL COMPLEXES | BIO LAYER PTY LTD (AU) | 2013-06-19 | — | — | EP | claimed |
| US-7881871-B2 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2011-02-01 | — | — | US | claimed |
| EP-1700244-A4 | A METHOD FOR DESIGNING SURFACES | BIO LAYER PTY LTD (AU) | 2009-07-08 | — | — | EP | claimed |
| US-20070099235-A1 | Method for designing surfaces | BIO-LAYER PTY LIMITED (AU) | 2007-05-03 | — | — | US | claimed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | claimed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | claimed |
| US-20160103126-A1 | USE OF METAL COMPLEXES | ANTEO TECHNOLOGIES PTY LTD (AU) | 2016-04-14 | — | — | US | disclosed |
| US-9234891-B2 | Use of metal complexes | ANTEO TECHNOLOGIES PTY LTD (AU) | 2016-01-12 | — | — | US | disclosed |
| EP-1773866-B1 | USE OF METAL COMPLEXES | BIO LAYER PTY LTD (AU) | 2013-06-19 | — | — | EP | disclosed |
| US-8273403-B2 | Generation of surface coating diversity | BIO-LAYER PTY LTD. (AU) | 2012-09-25 | — | — | US | disclosed |
| US-20120214973-A1 | USE OF METAL COMPLEXES | BIO-LAYER PTY LIMITED (AU) | 2012-08-23 | — | — | US | disclosed |
| US-8168445-B2 | Use of metal complexes | BIO-LAYER PTY LIMITED (AU) | 2012-05-01 | — | — | US | disclosed |
| EP-1534755-B1 | GENERATION OF SURFACE COATING DIVERSITY | BIO LAYER PTY LTD (AU) | 2011-10-12 | — | — | EP | disclosed |
| EP-1700244-A1 | A METHOD FOR DESIGNING SURFACES | Bio-Layer Pty Limited (AU) | 2006-09-13 | — | — | EP | disclosed |
| US-20060083858-A1 | Generation of surface coating diversity | ANTEO TECHNOLOGIES PTY LTD (AU) | 2006-04-20 | — | — | US | disclosed |
| WO-2006002472-A1 | USE OF METAL COMPLEXES | BIO-LAYER PTY LTD (AU) | 2006-01-12 | — | — | WO | disclosed |
| EP-1534755-A4 | GENERATION OF SURFACE COATING DIVERSITY | BIO LAYER PTY LTD (AU) | 2005-08-17 | — | — | EP | disclosed |
| WO-2005057462-A1 | A METHOD FOR DESIGNING SURFACES | BIO-LAYER PTY LIMITED (AU) | 2005-06-23 | — | — | WO | disclosed |
| EP-1534755-A1 | GENERATION OF SURFACE COATING DIVERSITY | Bio-Layer Pty Limited (AU) | 2005-06-01 | — | — | EP | disclosed |
| WO-2003095494-A1 | GENERATION OF SURFACE COATING DIVERSITY | BIO-LAYER PTY LIMITED (AU) | 2003-11-20 | — | — | WO | disclosed |