Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295983 | 0.97 | MAPT (0.44) | MAPTKMT2AATMKDM4EAPP | |
| SCHEMBL12296002 | 0.97 | MAPT (0.44) | MAPTKMT2AATMKDM4EAPP | |
| SCHEMBL1323237 | 0.90 | MAPT (0.49) | MAPTKMT2AATMKDM4EAPP | |
| SCHEMBL12327945 | 0.80 | HDAC1 (0.45) | KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12328264 | 0.80 | SIGMAR1 (0.46) | — | |
| SCHEMBL2632438 | 0.80 | MET (0.38) | MAPTKMT2AATMKDM4EAPP | |
| SCHEMBL16481554 | 0.80 | CYP1A2 (0.54) | KMT2AAPPCYP19A1CYP1A2CYP3A4 | |
| SCHEMBL2632620 | 0.80 | CHRM5 (0.42) | MAPTKMT2AATMKDM4EAPP | |
| SCHEMBL13917147 | 0.80 | MAPT (0.47) | MAPTKMT2AATMKDM4ESTAT3 | |
| SCHEMBL12296056 | 0.78 | BCHE (0.50) | KMT2AKDM4EAPPCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022098-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2011-09-20 | — | — | US | disclosed |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | disclosed |
| US-7705036-B2 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2010-04-27 | — | — | US | disclosed |
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | CARDIOME PHARMA CORP. (CA) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088075-A1 | Deuterated aminocyclohexyl ether compounds and processes for preparing same | DDC, HDHD5, DDT | MAPT 3508/4885KMT2A 870/4885ATM 2258/4885 |
| US-20100152276-A1 | DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME | DDC, HDHD5, DDT | MAPT 3508/4885KMT2A 870/4885ATM 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.